Publications

103. M. S. Aktar, N. K. Dhanvantari Madhuresh, R. A. Ghiladi and S. Franzen “The Role of Proton-Coupled Electron Transfer from Protein to Heme in Dehaloperoxidase” BBA Proteins Proteom. 2025, 1873, 141053.

102. M. S. Aktar, V. de Serrano, R. A. Ghiladi and S. Franzen “Structural Comparison of Substrate Binding Sites in Dehaloperoxidase A and B” Biochem. 2024, 63, 1761-1773.

101. W.-W. Deng, B. Sun, H. Yang, X.-J. Hou, Y.-J. Zhang, T.-X. Gan, X.-Y. Cheng, A. Yuan, X.-Y. Dong, C.-Y. Zhou, Y. Deng, Y. Xiao, R. A. Ghiladi, H. Li and J. Wang “A Novel Optimization Strategy for Extraction Antioxidant Components from Lonicerae Japonicae Flos Based on Tailored Deep Eutectic Solvents and Application for Quality Evaluation” Separations 2024, 11, 189.

100. Y. Xiao, W. Xiang, X. Ma, D. Gao, H. Bayram, G. H. Lorimer, R. A. Ghiladi, Z. Xie and J. Wang “HemN2 Regulates the Virulence of Pseudomonas donghuensis HYS through 7-Hydroxytropolone Synthesis and Oxidative Stress” Biology 2024, 13, 373.

99. Z. Campbell, C. R. Ghareeb, S. Baro, J. Mauthe, G. McColgan, A. Amassian, F. Scholle, R. A. Ghiladi, M. Abolhasani and E. C. Dickey “Facile Synthesis of Cu-doped TiO2 Particles for Accelerated Visible Light-Driven Antiviral and Antibacterial Inactivation” ACS Appl. Engin. Mater. 2024, 2, 1411–1423.

98. H. Zhou, R. Zhu, Y. Xia, X. Zhang, Z. Wang, G. H. Lorimer, R. A. Ghiladi, H. Bayram and J. Wang “Neuropeptides affecting social behavior in mammals: Oxytocin” Peptides 2024, 177, 171223.

97. J. Lv, H. Tian, L. Pan, Z. Chen, M. Li, R. A. Ghiladi, Z. Qin and X. Yin “Biomass derived carbon dots with antibacterial and anti-inflammatory properties for the treatment of wound healing” Chem. Eng. Sci. 2024, 295, 120084.

96. J. M. Gonzalez-Delgado, P. M. Thompson, W. Andralojc, Z. Gdaniec, R. A. Ghiladi and S. Franzen “Comparison of the Backbone Dynamics of Dehaloperoxidase-Hemoglobin Isoenzymes” J. Phys. Chem. B 2024, 128, 3383-3397.

95. A. Shi, D. Liu, H. Wu, R. Zhu, Y. Deng, L. Yao, Y. Xiao, G. H. Lorimer, R. A. Ghiladi, X. Xu, R. Zhang, H. Xu and J. Wang “Serum binding folate receptor autoantibodies lower in autistic boys and positively-correlated with folate” Biomed. Pharmacother. 2024, 172, 116191.

94. C. Jiang, F. Scholle, F. Jin, Q. Wei, Q. Wang and R. A. Ghiladi “Chlorophyllin as a Photosensitizer in Photodynamic Antimicrobial Materials” Cellulose 2024, in press.

93. L. Wu, N. Yang, M. Guo, D. D. Zhang, R. A. Ghiladi, H. Bayram and J. Wang “The role of sound stimulation in production of plant secondary metabolites” Nat. Prod. Bioprospect. 2023, 13, 40.

92. K. M. Wells, Y. Ciftci, B. S. T. Peddinti, R. A. Ghiladi, G. Vediyappan, R. J. Spontak and R. Govind “Preventing the Spread of Life-Threatening Gastrointestinal Microbes on the Surface of a Continuously Self-Disinfecting Block Polymer” J. Colloid Interface Sci. 2023, 652, 718-726.

91. M. S. Aktar, V. de Serrano, R. A. Ghiladi and S. Franzen “Comparative Study of the Binding and Activation of 2,4-Dichlorophenol by Dehaloperoxidase A and B” J. Inorg. Biochem. 2023, 247, 112332.

90. K. Wells, M. Miller, R. A. Ghiladi and R. J. Spontak “Fast Bacterial Inactivation Kinetics on an Inherently Antimicrobial Anionic Block Polymer” ACS Appl. Engr. Mater. 2023, 1, 1467-1472.

89. C. Jiang, S. Dejarnette, W. Chen, F. Scholle, Q. Wang and R. A. Ghiladi “Color-Variable Dual-Dyed Photodynamic Antimicrobial Polyethylene Terephthalate (PET)/Cotton Blended Fabrics” Photochem. Photobiol. Sci. 2023, 22, 1573-1590.

88. W.-w. Deng, C.-r. Zang, Q.-c. Li, B. Sun, X.-p. Mei, L. Bai., X.-m. Shang, Y. Deng, Y-.q. Xiao, R. A. Ghiladi, G. H. Lorimer, X.-j. Zhang and J. Wang “Hydrothermally Derived Green Carbon Dots from Broccoli Water Extracts: Decreased Toxicity, Enhanced Free-Radical Scavenging, and Anti-Inflammatory Performance” ACS Biomater. Sci. Eng. 2023, 9, 1307-1319.

87. W.-w. Deng, X.-p. Mei, Z.-j. Cheng, T.-x. Gan, X. Tian, J.-n. Hu, C.-r. Zang, B. Sun, J. Wu, Y. Deng, R. A. Ghiladi, G. H. Lorimer, G. Keceli and J. Wang “Extraction of weak hydrophobic sulforaphane from broccoli by salting-out assisted hydrophobic deep eutectic solvent extraction” Food Chem. 2022, 405, 134817.

86. Tian, J. Hong, C. Li, Y. Qiu, M. Li, Z. Qin, R. A. Ghiladi and X. Yin “Electrospinning membranes with Au@carbon dots: Low toxicity and efficient antibacterial photothermal therapy” Biomaterials Advances 2022, 142, 213155.

85. D. Yun, V. de Serrano and R. A. Ghiladi “Oxidation of Bisphenol A (BPA) and Related Compounds by the Multifunctional Catalytic Globin Dehaloperoxidase” J. Inorg. Biochem. 2022, 238, 112020.

84. T. Malewschik, L. M. Carey, V. de Serrano and R. A. Ghiladi “Bridging the Functional Gap Between Reactivity and Inhibition in Dehaloperoxidase B from Amphitrite ornata: Mechanistic and Structural Studies with 2,4- and 2,6-Dihalophenols” J. Inorg. Biochem. 2022, 236, 111944.

83. B. Peddinti, R. A. Ghiladi, and R. J. Spontak “Next-Generation Stimuli-Responsive Antimicrobial Coatings with Broad-Spectrum Efficacy,” in Handbook of Smart Polymer Coatings and Films for the 21st Century (P. Zarras, Y. Wei, and M.D. Soucek, eds.), Wiley, New York, 2022, in press.

82. T. Moreno-Chicanoa, L. M. Carey, D Axford, J. H. Beale, R. B. Doak, H. Duyvesteyn, A. Ebrahim, R. W. Henning, D. C. F. Monteiro, D. A. Myles, S. Owada, D. A. Sherrell, M. Straw, V. Šrajer, H. Sugimoto, K. Tono, T. Tosha, I. Tews, M. Trebbin, R. W. Strange, K. Weiss, J. A. R. Worrall, F. Meilleur, R. L. Owen, R. A. Ghiladi and M. A. Hough “Complementarity of Neutron, XFEL and Synchrotron Crystallography for Defining the Structures of Metalloenzymes at Room Temperature” IUCrJ, 2022, 9, 610-624.

81. C. V. Popescu, T. Dinh, H. Chen, D. Miller, A. Washburn, A. McGuire, R. Dumarieh, J. D’Antonio and R. A. Ghiladi “Mössbauer studies of the ferryl, ferrous and ferric states of dehaloperoxidase from A. ornata” J. Inorg. Biochem. 2022, 234, 111867.

80. F. Jin, S. Liao, Q. Wang, H. Shen, C. Jiang, J. Zhang, Q. Wei and R. A. Ghiladi “Dual-Functionalized Luminescent/Photodynamic Composite Fabrics: Synergistic Antibacterial Activity for Self-Disinfecting Textiles” Appl. Surf. Sci. 2022, 587, 152737.

79. H. Shen, S. Liao, C. Jiang, J. Zhang, Q. Wei, R. A. Ghiladi and Q. Wang “In situ grown bacterial cellulose/MoS₂ composites for multi-contaminant wastewater treatment and bacteria inactivation” Carbohydr. Polym. 2022, 277, 118853.

78. J. Wang, F. Mei, L. Bai, S. Zhou, D. Liu, L. Yao, A. Ahluwalia, R. A. Ghiladi, L. Su, T. Shu, M. Gong, X. Wang, L. Zhu, K. Cai and X. Zhang “Serum nitrite and nitrate: A potential biomarker for post-covid-19 complications?” Free Radic. Biol. Med. 2021, 175, 216-225.

77. H. Shen, C. Jiang, W. Li, Q. Wei, R. A. Ghiladi and Q. Wang “Synergistic Photodynamic and Photothermal Antibacterial Activity of In Situ Grown Bacterial Cellulose/MoS₂-Chitosan Nanocomposite Materials with Visible Light Illumination” ACS Appl. Mater. Interfaces 2021, 13, 31193–31205.

76. C. R. Ghareeb, B. S. T. Peddinti, S. C. Kisthardt, F. Scholle, R. J. Spontak and R. A. Ghiladi “Towards Universal Photodynamic Coatings for Infection Control” Front. Med. 2021, 8, 657837.

75. M. K. Thompson, M. R. Shay, V. de Serrano, R. Dumarieh, R. A. Ghiladi and S. Franzen “A New Inhibition Mechanism in the Multifunctional Catalytic Hemoglobin Dehaloperoxidase as Revealed by the DHP A(V59W) Mutant: A Spectroscopic and Crystallographic Study” J. Porphyr. Phthalocyanines 2021, 25, 756–771.

74. W. Nong, J. Wu, R. A. Ghiladi and Y. Guan “The Structural Appeal of Metal-Organic Frameworks in Antimicrobial Applications” Coord. Chem. Rev. 2021, 442, 214007.

73. T. Malewschik and R. A. Ghiladi “Dehaloperoxidase: An Enzymatic Swiss Army Knife” Coord. Chem. Rev. 2021, 441, 213976.

72. B. Peddinti, S. N. Downs, J. Yan, S. D. Smith, R. A. Ghiladi, V. Mhetar, R. Tocchetto, A. Griffiths, F. Scholle, and R. Spontak “Rapid and Repetitive Inactivation of SARS-CoV-2 and Human Coronavirus on Self-Disinfecting Anionic Polymers” Adv. Sci., 2021, 2003503.

71. W. Fang, J. Jiang, L. Su, T. Shu, H. Liu, S. Lai, R. A. Ghiladi and J. Wang “The role of NO in COVID-19 and potential therapeutic strategies” Free Radic. Biol. Med. 2021, 163, 153-162.

70. B. Peddinti, N. Morales-Gagnon, B. Pourdeyhimi, F. Scholle, R. Spontak and R. A. Ghiladi “Photodynamic Coatings on Polymer Microfibers for Pathogen Inactivation: Effects of Application Method and Composition” ACS Appl. Mater. Interfaces 2021, 13, 155-163.

69. B. Sun, Y.-L. Zheng, S.-K. Yang, J.-R. Zhang, X.-Y. Cheng, R. A. Ghiladi, Z. Ma, J. Wang, W.-W. Deng “One-pot method based on deep eutectic solvent for extraction and conversion of polydatin to resveratrol from Polygonum cuspidatum” Food Chem. 2021, 128498.

68. T. Wang, H. Ke, S. Chen, J. Wang, W. Yang, X. Cao, J. Liu, Q. Wei, R. A. Ghiladi and Q. Wang “Porous Protoporphyrin IX-Embedded Cellulose Diacetate Electrospun Microfibers in Antimicrobial Photodynamic Inactivation“ Mater. Sci. Eng. C, 2021, 111502.

67. T. Wang, W. Chen, T. Dong, Z. Lv, S. Zheng, X. Cao, Q. Wei, R. A. Ghiladi, and Q. Wang “Color-Variable Photodynamic Antimicrobial Wool/Acrylic Blended Fabrics” Materials 2020, 13, 4141.

66. X. Nie, C. Jiang, S. Wu, W. Chen, P. Lva, Q. Wang, J. Liu, C. Narh, X. Cao, R. A. Ghiladi, and Q. Wei “Carbon quantum dots: A bright future as photosensitizers for in vitro antibacterial photodynamic inactivation” J. Photoch. Photobio. B, 2020, 206, 111864.

65. T. Wang, L. Xu, H. Shen, X. Cao, Q. Wei, R. A. Ghiladi, and Q. Wang “Photoinactivation of Bacteria by Hypocrellin-Grafted Bacterial Cellulose” Cellulose 2020, 27, 991-1007.

64. B. Peddinti, F. Scholle, R. A. Ghiladi and R. Spontak “Antimicrobial Thermoplastic Elastomers: Strategic Pathways for the Future of Broad-Spectrum Anti-Infective Materials” Rubber World 2019, 161, 67-77.

63. E. Feese, Hanna S. Gracz, Paul D. Boyle and R. A. Ghiladi “Towards Microbe-targeted Photosensitizers: Synthesis, Characterization and In vitro Photodynamic Inactivation of the Tuberculosis Model Pathogen M. smegmatis by Porphyrin-Peptide Conjugates” J. Porphyr. Phthalocyanines 2019, 23, 1414-1439.

62. T. Malewschik, V. de Serrano, A. H. McGuire and R. A. Ghiladi “The Multifunctional Globin Dehaloperoxidase Strikes Again: Simultaneous Peroxidase and Peroxygenase Mechanisms in the Oxidation of EPA Pollutants” Arch. Biochem. Biophys. 2019, 673, 108079.

61. T. Moreno-Chicano, A. Ebrahim, D. Axford, M. V. Appleby, J. Beale, A. K. Chaplin, H. M. E. Duyvesteyn, R. A. Ghiladi, S. Owada, D. A. Sherrell, R. W. Strange, H. Sugimoto, K. Tono, J. A. R. Worrall, R. L. Owen and M. A. Hough “High Throughput Structures of Protein-Ligand Complexes at Room Temperature using Serial Femtosecond Crystallography” IUCrJ 2019, 6, 1074–1085.

60. W. Chen, J. Chen, L. Li, X. Wang, Q. Wei, R. A. Ghiladi, and Q. Wang “Wool/Acrylic Blended Fabrics as Next Generation Photodynamic Antimicrobial Materials” ACS Appl. Mater. Interfaces 2019, 11, 29557−29568.

59. B. Peddinti, F. Scholle, R. A. Ghiladi and R. Spontak “Inherently Self-Sterilizing Charged Multiblock Polymers that Kill Drug-Resistant Microbes in Minutes” Materials Horizons 2019, 6, 2056-2062.
(see the highlights of this paper in Chemistry World here, in C&E News here, and by the NCSU News Service here)

58. K. R. Stoll, F. Scholle, J. Zhu, X. Zhang and R. A. Ghiladi, “BODIPY-Embedded Electrospun Materials in Antimicrobial Photodynamic Inactivation,” Photochem. Photobiol. Sci. 2019, 18, 1923-1932 (invited).

57. D. R. Alvarado, D. S. Argyropoulos, F. Scholle, B. Peddinti and R. A. Ghiladi, “A Facile Strategy for Photoactive Nanocellulose-based Antimicrobial Materials,” Green Chemistry 2019, 21, 3424-3435.

56. C. Jiang, F. Scholle and R. A. Ghiladi, “Mn-doped Zn/S quantum dots as photosensitizers for antimicrobial photodynamic inactivation,” Proc. S.P.I.E. 2019, vol. 10863, Photonic Diagnosis and Treatment of Infections and Inflammatory Diseases II, 108630Q; DOI: 10.1117/12.2510934.

55. P. Chariou, L. Wang, C. Desai, J. Park, L. K. Robbins, H. A. von Recum, R. A. Ghiladi and N. F. Steinmetz “Let There Be Light: Targeted Photodynamic Therapy Using High Aspect Ratio Plant Viral Nanoparticles” Macromol. Biosci. 2019, 1800407.

54. B. Peddinti, F. Scholle, R. A. Ghiladi and R. Spontak “Photodynamic Polymers as Comprehensive Anti-Infective Materials: Staying Ahead of a Growing Global Threat” ACS Appl. Mater. Interfaces 2018, 10, 25955-25959.

53. A. McGuire, L. M. Carey, V. de Serrano, S. Dali and R. A. Ghiladi “Peroxidase vs. Peroxygenase Activity: Substrate Substituent Effects as Modulators of Enzyme Function in the Multifunctional Catalytic Globin Dehaloperoxidase” Biochemistry 2018, 57, 4455-4468.

52. W. Chen, W. Wang, X. Ge, Q. Wei, R. A. Ghiladi, and Q. Wang “Photo-Oxidation Properties of Photosensitizer/Direct Dye Patterned Polyester/Cotton Fabrics” Fiber Polym. 2018, 19, 1687–1693.

51. Q. Wang, W. Chen, Q. Zhang, R. A. Ghiladi and Q. Wei “Preparation of Photodynamic P(MMA-co-MAA) Composite Nanofibers Doped with MMT: A Facile Method for Increasing Antimicrobial Efficiency” Appl. Surf. Sci. 2018, 457, 247-255.

50. J. Dong, R. A. Ghiladi, Q. Wang, Y. Cai, and Q. Wei “Protoporphyrin-IX Conjugated Cellulose Nanofibers that Exhibit High Antibacterial Photodynamic Inactivation Efficacy” Nanotechnology 2018, 29, 265601.

49. J. Dong, R. A. Ghiladi, Q. Wang, Y. Cai, and Q. Wei “Protoporphyrin-IX Conjugated Bacterial Cellulose via Diamine Spacer Arms with Specific Antibacterial Photodynamic Inactivation Against Escherichia coli” Cellulose 2018, 25, 1673–1686.

48. L. M. Carey, K.-b. Kim, N. McCombs, P. Swartz, C. Kim, and R. A. Ghiladi “Selective Tuning of Activity in a Multifunctional Enzyme as Revealed in the F21W Mutant of Dehaloperoxidase B from Amphitrite ornata” J. Biol. Inorg. Chem. 2018,23, 209-219.

47. L. M. Carey, R. Gavenko, D. A. Svistunenko, and R. A. Ghiladi “How Nature Tunes Isoenzyme Activity in the Multifunctional Catalytic Globin Dehaloperoxidase from Amphitrite ornata” BBA Proteins Proteom. 2018, 1866, 230–241.

46. H. Masarapu, B. Patel, P. Chariou, H. Hu, N. Gulati, B. L. Carpenter, R. A. Ghiladi, S. Shukla, and N. F. Steinmetz “Physalis mottle virus-like particles as nanocarriers for imaging reagents and drugs” Biomacromolecules 2017, 18, 4141–4153.

45. N. L. McCombs, T. Smirnova, and R. A. Ghiladi “Oxidation of Pyrrole by Dehaloperoxidase-Hemoglobin: Chemoenzymatic Synthesis of Pyrrolin-2-Ones” Catal. Sci. Technol. 2017, 7, 3104-3118.

44. J. D. Wallat, K. Wek, P. Chariou, B. L. Carpenter, R. A. Ghiladi, N. F. Steinmetz and J. K. Pokorski “Fluorinated Polymer-Photosensitizer Conjugates Enable Improved Generation of ROS for Anticancer Photodynamic Therapy” Polymer Chem. 2017, 8, 3195-3202.

43. N. L. McCombs, T. Moreno-Chicano, L. M. Carey, S. Franzen, M. A. Hough, and R. A. Ghiladi “Interaction of Azole-based Environmental Pollutants with the Coelomic Hemoglobin from Amphitrite ornata: a Molecular Basis for Toxicity” Biochemistry 2017, 56, 2294–2303.

42. X. Du, L. A. Lucia, and R. A. Ghiladi “Development of an efficient and economical pretreatment sequence for the enzymatic saccharification of loblolly pine wood” ACS Sustainable Chem. Eng. 2016, 4, 3669–3678.

41. S. L. Stanley, F. Scholle, J. Zhu, Y. Lu, X. Zhang, X. Situ, and R. A. Ghiladi “Photosensitizer-Embedded Polyacrylonitrile Nanofibers as an Antimicrobial Non-Woven Textile” Nanomaterials2016, 6, 77.

40. N. L. McCombs, L. M. Carey, J. D’Antonio, D. A. Barrios, and R. A. Ghiladi “Non-microbial Nitrophenol Degradation via Peroxygenase Activity of Dehaloperoxidase-Hemoglobin from Amphitrite ornata” Biochemistry 2016, 55, 2465–2478.

39. A. M. Wen, P. Cao, K. L. Lee, K. Pangilinan, B. L. Carpenter, R. A. Ghiladi, R. C. Advincula, and N. F. Steinmetz “Utilizing viral nanoparticle/dendron hybrid conjugates in photodynamic therapy for dual delivery to macrophages and cancer cells” Bioconjugate Chem. 2016, 27, 1227–1235.

38. K. L. Lee, B. L. Carpenter, A. M. Wen, R. A. Ghiladi, and N. F. Steinmetz “A TMV-based Photosensitizer for Imaging and Treatment of Aggressive Melanoma” ACS Biomater. Sci. Eng.2016, 2, 838–844.

37. X. Du, L. A. Lucia, and R. A. Ghiladi “A Novel Approach for the Rapid Preparation of Monophasic Microemulsions that Facilitates the Penetration of Woody Biomass” ACS Sustainable Chem. Eng. 2016, 4, 1665-1672.

36. S. Franzen, R. A. Ghiladi, L. Lebioda, and J. Dawson “Chapter 10: Multi-functional hemoglobin dehaloperoxidases” in Heme Peroxidases; The Royal Society of Chemistry: 2015, p 218-244 (invited chapter).

35. B. L. Carpenter, F. Scholle, H. Sadeghifar, A. J. Francis, J. Boltersdorf, W. W. Weare, D. S. Argyropoulos, P. A. Maggard, and R. A. Ghiladi “Synthesis, Characterization, and Antimicrobial Efficacy of Photomicrobicidal Cellulose Paper” Biomacromolecules 2015, 16, 2482-2492.

34. B. L. Carpenter, X. Situ, F. Scholle, J. Bartelmess, W. W. Weare, and R. A. Ghiladi “Antiviral, Antifungal and Antibacterial Activities of a BODIPY-based Photosensitizer” Molecules 2015, 20, 10604-10621 (invited).

33. D. K. Muli, B. L. Carpenter, M. Mayukh, R. A. Ghiladi, D. V. McGrath “Dendritic near-IR absorbing zinc phthalocyanines for antimicrobial photodynamic therapy” Tetrahedron Lett. 2015, 56, 3541–3545.

32. D. Barrios, J. D’Antonio, N. L. McCombs, J. Zhao, S. Franzen, A. Schmidt, L. Sombers, and R. A. Ghiladi “Peroxygenase and Oxidase Activities of Dehaloperoxidase-Hemoglobin from Amphitrite ornata” J. Am. Chem. Soc. 2014, 136, 7914-7925.

31. R. Dumarieh, J. D’Antonio, A. Liang, T. Smirnova, D. A. Svistunenko, and R. A. Ghiladi “Tyrosyl Radicals in Dehaloperoxidase: How Nature Deals with Evolving an Oxygen Binding Globin to a Biologically-Relevant Peroxidase” J. Biol. Chem. 2013, 288, 33470–33482.

30. J. Zhao, V. de Serrano, R. Dumarieh, R. A. Ghiladi, M. K. Thompson, and S. Franzen “The Role of the Distal Histidine in H₂O₂ Activation and Heme Protection in Both Peroxidase and Globin Functions” J. Phys. Chem. 2012, 116, 12065-12077.

29. B. L. Carpenter, E. Feese, H. Sadeghifar, D. S. Argyropoulos, and R. A. Ghiladi “Porphyrin-Cellulose Nanocrystals: A Photobactericidal Material that Exhibits Broad Spectrum Antimicrobial Activity” Photochem. Photobiol. 2012, 88, 527-536 (invited).

28. D. A. Svistunenko, J. Worrall, S. Chugh, S. Haigh, R. A. Ghiladi, and P. Nicholls “Ferric haem forms of Mycobacterium tuberculosis catalase-peroxidase probed by EPR spectroscopy: their stability and interplay with pH” Biochimie 2012, 94, 1274-1280.

27. S. Franzen, K. Sasan, B. E. Sturgeon, B. J. Lyon, B. Batternberg, H. Gracz, R. Dumarieh, and R. A. Ghiladi “Non-Photochemical Base-Catalyzed Hydroxylation of 2,6-Dichloroquinone by H₂O₂ Occurs by a Radical Mechanism” J. Phys. Chem. B 2012, 116, 1666-1676.

26. S. Franzen, M. K. Thompson, and R. A. Ghiladi “The Dehaloperoxidase Paradox” Biochim. Biophys. Acta. 2012, 1824, 578-588.

25. R. A. Ghiladi, A. L. Rheingold, M. A. Siegler, and K. D. Karlin “Synthesis and characterization of new trinuclear copper complexes” Inorg. Chim. Acta 2012, 389, 131-137.

24. E. L. D’Antonio, J. D’Antonio, V. De Serrano, H. Gracz, M. K. Thompson, R. A. Ghiladi, E. F. Bowden, and S. Franzen “Functional Consequences of the Creation of an Asp-His-Fe Triad in a 3/3 Globin.” Biochemistry 2011, 50, 9664-9680.

23. E. Feese, H. Sadeghifar, H. Gracz, D. S. Argyropoulos, and R. A. Ghiladi “Photobactericidal Porphyrin-Cellulose Nanocrystals: Synthesis, Characterization and Antimicrobial Properties” Biomacromolecules 2011, 12, 3528-3539.

22. J. D’Antonio and R. A. Ghiladi “Reactivity of Deoxy- and Oxyferrous Dehaloperoxidase B from Amphitrite ornata: Identification of Compound II and its Ferrous-Hydroperoxide Precursor” Biochemistry 2011, 50, 5999-6011.

21. M. K. Thompson, S. Franzen, R. A. Ghiladi, B. Reeder, and D. A. Svistunenko “Compound ES of Dehaloperoxidase Decays via Two Alternative Pathways Depending on the Conformation of the Distal Histidine” J. Am. Chem. Soc., 2010, 132, 17501-17510.

20. J. D’Antonio, E. L. D’Antonio, M. K. Thompson, E. F. Bowden, S. Franzen, T. Smirnova, and R. A. Ghiladi “Spectroscopic and Mechanistic Investigations of Dehaloperoxidase B from Amphitrite ornata” Biochemistry 2010, 49, 6600-6616.

19. V. De Serrano, J. D’Antonio, S. Franzen, and R. A. Ghiladi “Structure of Dehaloperoxidase B at 1.58 Å Resolution and Structural Characterization of the A/B Dimer from Amphitrite ornata” Acta Cryst. 2010, D66, 529-538.

18. C. E. Cade, A. C. Dlouhy, K. F. Medzihradszky, S. P. Salas-Castillo, and R. A. Ghiladi “Isoniazid-Resistance Conferring Mutations in Mycobacterium tuberculosis KatG: Catalase, Peroxidase, and INH-NADH Adduct Formation Activities” Protein Sci., 2010, 19, 458-474.

17. E. Feese and R. A. Ghiladi “Highly Efficient Photodynamic Inactivation of Mycobacterium smegmatis” J. Antimicrob. Chemother. 2009, 64, 782-785.

16. J. Feducia, R. Dumarieh, L. B. G. Gilvey, T. Smirnova, S. Franzen, and R. A. Ghiladi “Characterization of Dehaloperoxidase Compound ES and its Reactivity with Trihalophenols” Biochemistry 2009, 48, 995-1005.

15. D. Maiti, J. S. Woertink, R. A. Ghiladi, E. I. Solomon, and Karlin, K. D. “Molecular Oxygen and Sulfur Reactivity of a Cyclotriveratrylene Derived Trinuclear Copper(I) Complex” Inorg. Chem. 2009, 48, 8342-8356.

14. R. A. Ghiladi, E. Chufan, D. del Río, E. I. Solomon, C. Krebs, B. H. Huynh, H.-w. Huang, P. Moënne-Loccoz, S. Kaderli, M. Honecker, A. D. Zuberbühler, L. Marzilli, R. J. Cotter, and K. D. Karlin “Further Insights into the Spectroscopic Properties, Electronic Structure and Kinetics of Formation of the Heme-Peroxo-Copper Complex [(F₈TPP)Fe^III-(O₂^2–)-Cu^II(TMPA)]⁺” Inorg. Chem. 2007, 46, 3889-3902.

13. R. A. Ghiladi, K. F. Medzihradszky, and P. R. Ortiz de Montellano “The Role of the Met-Tyr-Trp Crosslink in Mycobacterium tuberculosis Catalase-Peroxidase (KatG) as Revealed by KatG(M255I)” Biochemistry 2005, 44, 15093-15105.

12. R. A. Ghiladi, K. F. Medzihradszky, F. M. Rusnak, and P. R. Ortiz de Montellano “Correlation Between Isoniazid Resistance and Superoxide Reactivity in Mycobacterium tuberculosis KatG” J. Am. Chem. Soc. 2005, 127, 13428-13442.

11. R. A. Ghiladi, G. M. Knudsen, K. F. Medzihradszky, and P. R. Ortiz de Montellano “The Met-Tyr-Trp cross-link in Mycobacterium tuberculosis Catalase-Peroxidase (KatG): Autocatalytic Formation and Effect on Enzyme Catalysis and Spectroscopic Properties” J. Biol. Chem. 2005, 280, 22651-22663.

10. R. A. Ghiladi, H.-w. Huang, P. Moënne-Loccoz, J. Stasser, N. J. Blackburn, A. S. Woods, R. J. Cotter, C. D. Incarvito, A. L. Rheingold, and K. D. Karlin “Heme-copper/dioxygen Adduct Formation Relevant to Cytochrome c Oxidase: Spectroscopic Characterization of [(⁶L)Fe^III-(O₂^2-)-Cu^II]⁺” J. Biol. Inorg. Chem. 2005, 10, 63-77.

9. R. A. Ghiladi, D. E. Cabelli, and P. R. Ortiz de Montellano “Superoxide Reactivity of KatG: Insights into Isoniazid Resistance Pathways in TB” J. Am. Chem. Soc. 2004, 126, 4722-4723.

8. D. W. Thompson, R. M. Kretzer, E. L. Lebeau, D. V. Scaltrio, R. A. Ghiladi, K.-C. Lam, A. L. Rheingold, K. D. Karlin, and G. J. Meyer “Synthesis, Characterization, and Laser Flash Photolysis Reactivity of a Reduced Carbonmonoxy Heme Complex” Inorg. Chem. 2003, 42, 5211-5218.

7. R. M. Kretzer, R. A. Ghiladi, E. L. Lebeau, H.-C. Liang, and K. D. Karlin “Synthesis and Characterization of Reduced Heme and Heme/Copper Carbonmonoxy Species” Inorg. Chem. 2003, 42, 3016-3025.

6. R. A. Ghiladi and K. D. Karlin “Low-Temperature UV-Visible and NMR Spectroscopic Investigations of O₂ Binding to (⁶L)Fe^II, a Ferrous Heme Bearing Covalently Tethered Axial Pyridine Ligands” Inorg. Chem. 2002, 41, 2400-2407.

5. R. A. Ghiladi, R. M. Kretzer, I. Guzei, A. L. Rheingold, Y.-M. Neuhold, K. R. Hatwell, A. D. Zuberbühler, and K. D. Karlin “(F₈TPP)Fe^II/O₂ Reactivity Studies {F₈TPP = Tetrakis(2,6-difluorophenyl)porphyrinate(2-)}: Spectroscopic (UV-Visible and NMR) and Kinetic Study of Solvent-Dependent (Fe/O₂ = 1:1 or 2:1) Reversible O₂-Reduction and Ferryl Formation” Inorg. Chem. 2001, 40, 5754-5767.

4. R. A. Ghiladi, K. R. Hatwell, K. D. Karlin, H.-w. Huang, P. Moënne-Loccoz, C. Krebs, B. H. Huynh, L. Marzilli, R. J. Cotter, S. Kaderli, and A. D. Zuberbühler “Dioxygen Reactivity of Mononuclear Heme and Copper Components Yielding A High-Spin Heme-Peroxo-Cu Complex” J. Am. Chem. Soc. 2001, 123, 6183-6184.

3. P. Moënne-Loccoz, O. M. H. Richter, H.-w. Huang, I. M. Wasser, R. A. Ghiladi, and K. D. Karlin “Nitric Oxide Reductase from Paracoccus Denitrificans Contains an Oxo-Bridged Heme/Non-Heme Diiron Center” J. Am. Chem. Soc. 2000, 122, 9344-9345.

2. R. A. Ghiladi, T. D. Ju, D.-H. Lee, P. Moënne-Loccoz, S. Kaderli, Y.-M. Neuhold, A. D. Zuberbühler, A. S. Woods, R. J. Cotter, and K. D. Karlin “Formation and Characterization of a High-Spin Heme-Copper (Peroxo) Complex” J. Am. Chem. Soc. 1999, 121, 9885-9886.

1. T. D. Ju, R. A. Ghiladi, D.-H. Lee, G. P. F. van Strijdonck, A. S. Woods, R. J. Cotter, V. G. Young Jr., and K. D. Karlin “Dioxygen Reactivity of Fully Reduced [LFe^II…Cu^I]⁺ Complexes Utilizing Tethered Tetraarylporphyrins: Active Site Models for Heme-Copper Oxidases” Inorg. Chem. 1999, 38, 2244-2245.